Do you have Crohn’s disease (CD)?
The CULTIVATE team is looking for people with CD to join a clinical research study assessing an
investigational drug.
Why participate?
✔ Potentially get access to the oral, once-daily, investigational drug at no cost
✔ Be monitored by gastrointestinal (GI) specialists
✔ Feel empowered
✔ Help advance CD research
Who can participate?
You may be able to take part in the study if you*
✔ Are 18 to 80 years of age
✔ Were diagnosed with moderately to severely active CD at least 3 months ago
✔ Did not respond to, are no longer responding to, or did not tolerate another CD therapy
*Other eligibility criteria apply
What else do I need to know?
You’ll get complete information: The study team will explain the possible benefits and risks of the
study.
Care and medication provided: All the investigational treatment and study-related care will be
provided to you at no cost.
Investigational treatment: Investigational drug versus placebo: During the study treatment period,
you will have a 2-in-3 chance of receiving the investigational drug and a 1-in-3 chance of receiving
the placebo. During the long-term extension study, all participants will receive the investigational
drug.
Participating countries in Europe:
Austria, Belarus, Belgium, Czech Rep., France, Germany, Israel, Italy,
Netherlands, Poland, Spain, Switzerland, United Kingdom
For more information on participating sites, please visit:
Austria
Hospitals:
(3001) - LKH - Universitaetsklinikum Graz
Investigator: Dr. Christoph Högenauer
Study Coordinator: Andrea Streit (andrea.streit@medunigraz.at, 0043 316 385 81157)
(3005) - Medizinische Universität Innsbruck
Investigator: Prof. Robert Koch (robert.koch@i-med.ac.at)
tudy Coordinator: Dr. Shadab Allipour (shadab.allipour@i-med.ac.at, 0043 512 504 81311)
(3006) - AKH - Medizinische Universität Wien
Investigator: Prof. Dr. Walter Reinisch
Study Coordinator: Patrick Schreiner (post_akh_i3m_ced@akhwien.at, 0043 1 40400 62450)
Belarus
Hospitals:
(57004) - Gomel Regional Clinical Hospital
Investigator: Dr. Elena Mikhailova (elena.mikhailova@tut.by, 375296465206)
Study Coordinator: Alina Sennikava (senalinusik@mail.ru, 375299318047)
(57005) - Vitebsk Regional Clinical Hospital
Investigator: Dr. Sergey Pimanov (pimanovs@tut.by, 375298996852)
Study Coordinator: Elena Dikareva (ruselikelena@mail.ru, 375333581988)
(57006) - Vitebsk Regional Clinical Specialized Center
Investigator: Dr. Henadz Yupatau (yupatovgi@gmail.com)
(57008) - Mogilev Hospital #1
Investigator: Dr. Sergey Gapanovich (gapanovich.ct@gmail.com, 375296904611)
(57010) - City Clinical Hospital #10, Minsk
Investigator: Dr. Volha Panes (olgabraschko@gmail.com, 375447489636)
Belgium
Hospitals:
(31002) – AZ Delta, Roeselare
Investigator: Dr. Filip Baert (filip.baert@azdelta.be, +3251237215)
Study Coordinator: Lien Decaesteker (lien.decaesteker@azdelta.be, +3251237512)
(31007) - UZ Leuven
Investigator: Prof Dr. S. Vermeire (severine.vermeire@uzleuven.be, 0032 16 344218)
Study Coordinator: Karen Rans (karen.rans@uzleuven.be, 0032 16 348856)
(31009) - AZ Sint-Lucas
Investigator: Prof. Harald Peeters (harald.peeters@azstlucas.be, 0032 (0)9 224 64 80)
Study Coordinator: Sophie Claeys (sophie.claeys@azstlucas.be, 0032 (0)9 224 51 70)
(31011) - Universitair Ziekenhuis Gent
Study Coordinator: 0032 (0)9 332 51 66
(31016) - CHU UCL Namur Site Godinne, Yvoir
Investigator: Dr. JF Rahier
Study Coordinator: Tasiaux Charlotte (s.tasiaux@chuuclnamur.uclouvain.be)
(31017) - AZ Maria Middelares
Investigator: Prof. Dr. P. Dewint
Study Coordinator: Laura Van Damme (laura.vandamme@azmmsj.be, 0032 (0)9 246 71 43)
Czech Republic
Hospitals:
(34013) - GASTRO JeKa, s.r.o., Klatovy, 33901
(34014) - PreventaMed s.r.o., Olomouc
Investigator: Dana Mohrova (mohrova@vilazdravi.cz, 420-6044-99100)
(34017) - Asclepiades - Interna Gastroenterologie s.r.o.
France*
Hospitals:
(35001) - Chru Nancy Brabois, Vandoeuvre les Nancy, Meurthe Et Moselle, 54511
(35002) - Chu Amiens Picardie-Sit Sud, Amiens Cedex, Somme
(35003) - Chu Lille, Hôpital Claude Huriez, Lille cedex, Nord, 59037
(35005) - Hopital Rangueil, Toulouse Cedex 09, Haute Garonne
Investigator: Dr. Gilletta Cyrielle (gilletta.c@chu-toulouse.fr, 0033 561322231)
Study Coordinator: Emilie Bergerau (bergereau.e@chu-toulouse.fr, 0033 561323080)
(35007) - CHU de Grenoble - Hôpital Nord, Grenoble
(35008) - CHU Nice - Hôpital de l'Archet 2 - URC Gastro-ènterologie, Nice
Investigator: Dr. Xavier Hebuterne (gastro.urc@chu-nice.fr)
(35009) - CHU Clermont Ferrand - Hôpital d'Estaing, Clermont-Ferrand Cedex 1
(35013) - Centre Hospitalier Départemental Les Oudairies
Study Coordinator: Maud Rosso (maud.rosso@ght85.fr, 0033 251446467)
(35015) - Hopital Saint Eloi Pole Digestif Hgea Recherche Clinique Rdc, Montpellier Cedex 5, Herault, 34295
(35016) - CHU Reims - Hôpital Robert Debré
Investigator: Dr. Guillaume Cadiot (gcadiot@chu-reims.fr, 03 26 78 84 41)
Study Coordinator: A. Gallaire (agallaire@chu-reims.fr, 03 26 78 42 23)
(35019) - Chu Besancon Hôpital Jean Minjoz, Besançon Cedex, Doubs, 25000
(35020) - CHU Saint Etienne - Hôpital Nord
Investigator: Dr. Xavier Roblin (xavier.roblin@chu-st-etienne.fr, 0033 4 77 82 91 19)
Study Coordinator: Nabila Boukhadra (nabila.boukhadra@chu-st-etienne.fr, 0033 4 77 82 92 12)
*It is important to discuss this possibility with your general practitioner/family doctor
Germany
Hospitals:
(36004) - Magen-Darm-Zentrum Remscheid, Remscheid
Investigator: Dr. med. Eric Joergensen (ericjoergensen@me.com, 0049 2191 890 1050)
Study Coordinator: Kathrin Schaupeter (studienkoordination@mdz-remscheid.de, 0049 2191 890 1056)
(36008) - Universitaetsklinikum Schleswig-Holstein - Campus Kiel
(36011) - Schwerpunktpraxis Bonn, Bonn
(36014) - Florence-Nightingale-Krankenhaus-Diakonie Kaiserswerth, Düsseldorf
(36015) - Johanna-Etienne-Krankenhaus, Neuss
(36017) - Universitaetsklinikum Augsburg
(36018) - Staedisches Klinikum Brandenburg, Brandenburg an der Havel, Brandenburg, 14770
(36019) - Medius Klinik Nuertingen, Nürtingen, Baden Wuerttemberg, 72622
(36020) - Gastroenterologie Opernstrasse, Kassel, Hessen, 34117
(36023) - Universitaetsklinikum Ulm
(36024) - Agaplesion Markus Krankenhaus gGmbH Medizinische Klinik I Studienzentrale, Frankfurt, Hessen, 60431
Study Coordinator: Christina Büttner (christina.buettner@agaplesion.de)
(36025) - Universitaetsklinikum Jena
(36027) - Universitaetsklinikum Freiburg
Israel
Hospitals:
(39002) - HaEmek Medical Center, Afula, Israel, 183411
(39004) - Chaim Sheba Medical Center, Ramat Gan, Israel, 5265602
(39006) - Shaare Zedek Medical Center, Jerusalem
Investigator: Prof. Eran Goldin (erang@szmc.org.il, 972 (0) 772260064)
(39008) - Wolfson Medical Center, Holon, Israel, 5822012
(39012) - Tel Aviv Sourasky Medical Center
Italy
Hospitals:
(40005) - Ospedale San Bortolo di Vicenza, Vicenza
Investigator: Dr. Paolo Pallini (paolo.pallini@aulss8.veneto.it)
(40007) - Ospedale di Circolo (U.O.C.) Gastroenterologia ed Endoscopia Digestiva, Rho, Milano, 20017
(40011) - Azienda Ospedaliero Universitaria Mater Domini
Investigator: Dr. Francesco Luzza (luzza@unicz.it, 0039 09613647113)
(40017) - Ospedale Sacro Cuore Don Calabria
(40018) - Azienda Ospedaliera Universitaria Integrata Verona (Ospedale Borgo Roma)
(40019) - Azienda Ospedaliera Ospedale Cannizzaro
(40021) - Azienda Ospedaliera Saverio De Bellis
Investigator: Dr. Mauro Mastronardi (mauro.mastronardi@irccsdebellis.it, 0039 0804994235)
Study Coordinator: Natalino Vena (natalino.vena@irccsdebellis.it, 0039 0804994379)
(40023) - Azienda Ospedaliero-Universitaria Sant 'Andrea UOC Malattie dell'a arato di erente, Rome, 00189
Investigator: Dr. Bruno Annibale (bruno.annibale@uniroma1.it, 0039 (0)6 33 775695)
Study Coordinator: Flavia Baccini (flavia.baccini@gmail.com, 0039 (0)6 33 775290)
(40025) - IRCCS Ospedale Casa Sollievo della Sofferenza, S.C. Gastroenterologia ed Endoscopia Digestiva, San Giovanni Rotondo, Foggia, 71013
Investigator: Dr. Fabrizio Bossa (f.bossa@operapadrepio.it, 0039 (0)882 410815)
Study Coordinator: Maria Guerra (mariaguerra.mg247@gmail.com, 0039 (0)882 410815)
(40026) - Fondazione IRCCS Policlinico San Matteo
(40029) - Ospedale San Raffaele, Milano
Netherlands
Hospitals:
(41004) - UMC Utrecht, Trialbureau MDL, Utrecht, 3508 GA
(41006) - Amsterdam UMC, location AMC, Amsterdam, 1105 AZ
(41008) - Leids Universitair Medisch Centrum
(41009) – Radboudumc, Nijmegen, 6525 GA
Poland
Hospitals:
(43001) – Centrum Zdrowia MDM, Warszawa, 00-635
(43002) – SOLUMED Centrum Medyczne, Poznan, Poland, 60-529
(43004) – DC-MED
(43005) - Karkonoskie Centrum Badan Klinicznych – Lexmedica, Jelenia Gora, 58-500
(43006) - Gabinet Lekarski Bartosz Korczowski
(43009) - Centrum Medyczne Medyk, Rzeszow, Poland, 35-236
(43020) - Centralny Szpital Kliniczny MSWiA w Warszawie
(43026) - Osrodek Badan Klinicznych Allmedica
Investigator: Dr. Mikolaj Krzyzanowski (mikolaj.krzyzanowski@gmail.com, 0048 600 616769)
Study Coordinator: Patrycja Lesnicka (patrycja.lesnicka@allmedica.pl, 0048 575 886613)
(43029) - IP Clinic, Lodz, 90-752
(43031) - Centrum Medyczne Grunwald, Poznan, 60-369
(43032) - Medicome Sp. z o.o., Oswiecim, 32-600
(43034) - Amicare Sp. z o.o. Sp.k, Lodz, 90-644
Study Coordinator: Maria Michalak (m.michalak@amicare.pl, 0048 42 6394944)
(43036) - Wip Warsaw Ibd Point, Warszawa, 00-728
(43037) - Landa-Specjalistyczne Gabinety Lekarskie, Krakow, Poland, 31-156
Investigator: Dr. Katarzyna Landa (landa@smo.com.pl)
Study Coordinator I: Justyna Targosz (targosz@smo.com.pl, 0048 508 790106)
Study Coordinator II: Julia Szczepanek (szczepanek@smo.com.pl, 0048 508 790106)
(43038) - Trialmed CRS, Piotrkow Trybunalski, 97-300
Study Coordinator: Piotr Pokojowczyk (piotr.pokojowczyk@wp.pl, 0048 510 945166)
(43039) - ETG Zamosc, Zamosc, 22-400
(43040) - PlanetMed sp. z o.o., Wroclaw, 52-210
(43041) - Specjalistyczne Gabinety Lekarskie Body Clinic, Warszawa, 03-712
(43042) - Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska, Wroclaw, 51-162
Study Coordinator: Katarzyna Okrzesa (okrzesa.katarzyna@cbk.wroc.pl, 0048 530 898161)
(43043) - Kiepury Clinic MAŁGORZATA JARNOT SPECJALISTYCZNA PRAKTYKA GINEKOLOGICZNO-POŁOŻNICZA
Spain
Hospitals:
(47005) - Hospital Universitario La Paz, Madrid, 28046
(47006) - Hospital Universitario de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Las Palmas, 35019
Investigator: Dr. Daniel Ceballos (investigacion.dig.negrino@gmail.com, 928 449676)
(47010) - Hospital General de Tomelloso, Tomelloso, Ciudad Real, 13700
Investigator: Dr. Alfredo J. Lucendo (ajlucendo@sescam.jccm.es)
Study Coordinator: Sousoles R. Tamarit (stamarit@sescam.jccm.es, 926 525928)
(47013) - Corporacio Sanitaria Parc Tauli
(47019) - Hospital Marina Baixa, Villajoyosa, Alicante, 03570
Switzerland
Hospitals:
(49004) - Inselspital - Universitaetsspital Bern
Investigator: Dr. Benjamin Misselwitz (benjamin.misselwitz@insel.ch)
Study Coordinator: Sandra Wyss (sandra.wyss@insel.ch)
(49008) - Universitaetsspital Basel
UK
Hospitals:
(52004) - Norfolk and Norwich University Hospital
(52005) - Yeovil District Hospital, Yeovil, Somerset, BA21 4AT
Investigator: Dr. Katie Smith
Study Coordinator: Amanda Roberts (clinical.research@ydh.nhs.uk, 01935 384854)
(52009) - Guys and St. Thomas NHS Foundation Trust, Lambeth, Greater London, SE1 7EH
(52011) - St James's University Hospital
(52012) - Central Middlesex Hospital
(52013) - Royal Liverpool University Hospital