CULTIVATE
Do you have Crohn’s disease (CD)?
The CULTIVATE team is looking for people with CD to join a clinical research study assessing an
investigational drug.
Why participate?
Potentially get access to the oral, once-daily, investigational drug at no cos
Be monitored by gastrointestinal (GI) specialists
Feel empowered
Help advance CD research
Who can participate?
You may be able to take part in the study if you*
Are 18 to 80 years of age
Were diagnosed with moderately to severely active CD at least 3 months ago
Did not respond to, are no longer responding to, or did not tolerate another CD therapy
*Other eligibility criteria apply
What else do I need to know?
You’ll get complete information: The study team will explain the possible benefits and risks of the
study.
Care and medication provided: All the investigational treatment and study-related care will be
provided to you at no cost.
Investigational treatment: Investigational drug versus placebo: During the study treatment period,
you will have a 2-in-3 chance of receiving the investigational drug and a 1-in-3 chance of receiving
the placebo. During the long-term extension study, all participants will receive the investigational
drug.
Participating countries in Europe:
Austria, Belarus, Belgium, Czech Rep., France, Germany, Israel, Italy,
Netherlands, Poland, Spain, Switzerland, United Kingdom
For more information on participating sites, please visit:
Austria
Hospitals:
(3001) - LKH - Universitaetsklinikum Graz
Investigator: Dr. Christoph Högenauer
Study Coordinator: Andrea Streit (andrea.streit@medunigraz.at, 0043 316 385 81157)
(3005) - Medizinische Universität Innsbruck
Investigator: Prof. Robert Koch (robert.koch@i-med.ac.at)
tudy Coordinator: Dr. Shadab Allipour (shadab.allipour@i-med.ac.at, 0043 512 504 81311)
(3006) - AKH - Medizinische Universität Wien
Investigator: Prof. Dr. Walter Reinisch
Study Coordinator: Patrick Schreiner (post_akh_i3m_ced@akhwien.at, 0043 1 40400 62450)
Belarus
Hospitals:
(57004) - Gomel Regional Clinical Hospital
Investigator: Dr. Elena Mikhailova (elena.mikhailova@tut.by, 375296465206)
Study Coordinator: Alina Sennikava (senalinusik@mail.ru, 375299318047)
(57005) - Vitebsk Regional Clinical Hospital
Investigator: Dr. Sergey Pimanov (pimanovs@tut.by, 375298996852)
Study Coordinator: Elena Dikareva (ruselikelena@mail.ru, 375333581988)
(57006) - Vitebsk Regional Clinical Specialized Center
Investigator: Dr. Henadz Yupatau (yupatovgi@gmail.com)
(57008) - Mogilev Hospital #1
Investigator: Dr. Sergey Gapanovich (gapanovich.ct@gmail.com, 375296904611)
(57010) - City Clinical Hospital #10, Minsk
Investigator: Dr. Volha Panes (olgabraschko@gmail.com, 375447489636)
Belgium
Hospitals:
(31002) – AZ Delta, Roeselare
Investigator: Dr. Filip Baert (filip.baert@azdelta.be, +3251237215)
Study Coordinator: Lien Decaesteker (lien.decaesteker@azdelta.be, +3251237512)
(31007) - UZ Leuven
Investigator: Prof Dr. S. Vermeire (severine.vermeire@uzleuven.be, 0032 16 344218)
Study Coordinator: Karen Rans (karen.rans@uzleuven.be, 0032 16 348856)
(31009) - AZ Sint-Lucas
Investigator: Prof. Harald Peeters (harald.peeters@azstlucas.be, 0032 (0)9 224 64 80)
Study Coordinator: Sophie Claeys (sophie.claeys@azstlucas.be, 0032 (0)9 224 51 70)
(31011) - Universitair Ziekenhuis Gent
Study Coordinator: 0032 (0)9 332 51 66
(31016) - CHU UCL Namur Site Godinne, Yvoir
Investigator: Dr. JF Rahier
Study Coordinator: Tasiaux Charlotte (s.tasiaux@chuuclnamur.uclouvain.be)
(31017) - AZ Maria Middelares
Investigator: Prof. Dr. P. Dewint
Study Coordinator: Laura Van Damme (laura.vandamme@azmmsj.be, 0032 (0)9 246 71 43)
Czech Republic
Hospitals:
(34013) - GASTRO JeKa, s.r.o., Klatovy, 33901
(34014) - PreventaMed s.r.o., Olomouc
Investigator: Dana Mohrova (mohrova@vilazdravi.cz, 420-6044-99100)
(34017) - Asclepiades - Interna Gastroenterologie s.r.o.
France*
Hospitals:
(35001) - Chru Nancy Brabois, Vandoeuvre les Nancy, Meurthe Et Moselle, 54511
(35002) - Chu Amiens Picardie-Sit Sud, Amiens Cedex, Somme
(35003) - Chu Lille, Hôpital Claude Huriez, Lille cedex, Nord, 59037
(35005) - Hopital Rangueil, Toulouse Cedex 09, Haute Garonne
Investigator: Dr. Gilletta Cyrielle (gilletta.c@chu-toulouse.fr, 0033 561322231)
Study Coordinator: Emilie Bergerau (bergereau.e@chu-toulouse.fr, 0033 561323080)
(35007) - CHU de Grenoble - Hôpital Nord, Grenoble
(35008) - CHU Nice - Hôpital de l'Archet 2 - URC Gastro-ènterologie, Nice
Investigator: Dr. Xavier Hebuterne (gastro.urc@chu-nice.fr)
(35009) - CHU Clermont Ferrand - Hôpital d'Estaing, Clermont-Ferrand Cedex 1
(35013) - Centre Hospitalier Départemental Les Oudairies
Study Coordinator: Maud Rosso (maud.rosso@ght85.fr, 0033 251446467)
(35015) - Hopital Saint Eloi Pole Digestif Hgea Recherche Clinique Rdc, Montpellier Cedex 5, Herault, 34295
(35016) - CHU Reims - Hôpital Robert Debré
Investigator: Dr. Guillaume Cadiot (gcadiot@chu-reims.fr, 03 26 78 84 41)
Study Coordinator: A. Gallaire (agallaire@chu-reims.fr, 03 26 78 42 23)
(35019) - Chu Besancon Hôpital Jean Minjoz, Besançon Cedex, Doubs, 25000
(35020) - CHU Saint Etienne - Hôpital Nord
Investigator: Dr. Xavier Roblin (xavier.roblin@chu-st-etienne.fr, 0033 4 77 82 91 19)
Study Coordinator: Nabila Boukhadra (nabila.boukhadra@chu-st-etienne.fr, 0033 4 77 82 92 12)
*It is important to discuss this possibility with your general practitioner/family doctor
Germany
Hospitals:
(36004) - Magen-Darm-Zentrum Remscheid, Remscheid
Investigator: Dr. med. Eric Joergensen (ericjoergensen@me.com, 0049 2191 890 1050)
Study Coordinator: Kathrin Schaupeter (studienkoordination@mdz-remscheid.de, 0049 2191 890 1056)
(36008) - Universitaetsklinikum Schleswig-Holstein - Campus Kiel
(36011) - Schwerpunktpraxis Bonn, Bonn
(36014) - Florence-Nightingale-Krankenhaus-Diakonie Kaiserswerth, Düsseldorf
(36015) - Johanna-Etienne-Krankenhaus, Neuss
(36017) - Universitaetsklinikum Augsburg
(36018) - Staedisches Klinikum Brandenburg, Brandenburg an der Havel, Brandenburg, 14770
(36019) - Medius Klinik Nuertingen, Nürtingen, Baden Wuerttemberg, 72622
(36020) - Gastroenterologie Opernstrasse, Kassel, Hessen, 34117
(36023) - Universitaetsklinikum Ulm
(36024) - Agaplesion Markus Krankenhaus gGmbH Medizinische Klinik I Studienzentrale, Frankfurt, Hessen, 60431
Study Coordinator: Christina Büttner (christina.buettner@agaplesion.de)
(36025) - Universitaetsklinikum Jena
(36027) - Universitaetsklinikum Freiburg
Israel
Hospitals:
(39002) - HaEmek Medical Center, Afula, Israel, 183411
(39004) - Chaim Sheba Medical Center, Ramat Gan, Israel, 5265602
(39006) - Shaare Zedek Medical Center, Jerusalem
Investigator: Prof. Eran Goldin (erang@szmc.org.il, 972 (0) 772260064)
(39008) - Wolfson Medical Center, Holon, Israel, 5822012
(39012) - Tel Aviv Sourasky Medical Center
Italy
Hospitals:
(40005) - Ospedale San Bortolo di Vicenza, Vicenza
Investigator: Dr. Paolo Pallini (paolo.pallini@aulss8.veneto.it)
(40007) - Ospedale di Circolo (U.O.C.) Gastroenterologia ed Endoscopia Digestiva, Rho, Milano, 20017
(40011) - Azienda Ospedaliero Universitaria Mater Domini
Investigator: Dr. Francesco Luzza (luzza@unicz.it, 0039 09613647113)
(40017) - Ospedale Sacro Cuore Don Calabria
(40018) - Azienda Ospedaliera Universitaria Integrata Verona (Ospedale Borgo Roma)
(40019) - Azienda Ospedaliera Ospedale Cannizzaro
(40021) - Azienda Ospedaliera Saverio De Bellis
Investigator: Dr. Mauro Mastronardi (mauro.mastronardi@irccsdebellis.it, 0039 0804994235)
Study Coordinator: Natalino Vena (natalino.vena@irccsdebellis.it, 0039 0804994379)
(40023) - Azienda Ospedaliero-Universitaria Sant 'Andrea UOC Malattie dell'a arato di erente, Rome, 00189
Investigator: Dr. Bruno Annibale (bruno.annibale@uniroma1.it, 0039 (0)6 33 775695)
Study Coordinator: Flavia Baccini (flavia.baccini@gmail.com, 0039 (0)6 33 775290)
(40025) - IRCCS Ospedale Casa Sollievo della Sofferenza, S.C. Gastroenterologia ed Endoscopia Digestiva, San Giovanni Rotondo, Foggia, 71013
Investigator: Dr. Fabrizio Bossa (f.bossa@operapadrepio.it, 0039 (0)882 410815)
Study Coordinator: Maria Guerra (mariaguerra.mg247@gmail.com, 0039 (0)882 410815)
(40026) - Fondazione IRCCS Policlinico San Matteo
(40029) - Ospedale San Raffaele, Milano
Netherlands
Hospitals:
(41004) - UMC Utrecht, Trialbureau MDL, Utrecht, 3508 GA
(41006) - Amsterdam UMC, location AMC, Amsterdam, 1105 AZ
(41008) - Leids Universitair Medisch Centrum
(41009) – Radboudumc, Nijmegen, 6525 GA
Poland
Hospitals:
(43001) – Centrum Zdrowia MDM, Warszawa, 00-635
(43002) – SOLUMED Centrum Medyczne, Poznan, Poland, 60-529
(43004) – DC-MED
(43005) - Karkonoskie Centrum Badan Klinicznych – Lexmedica, Jelenia Gora, 58-500
(43006) - Gabinet Lekarski Bartosz Korczowski
(43009) - Centrum Medyczne Medyk, Rzeszow, Poland, 35-236
(43020) - Centralny Szpital Kliniczny MSWiA w Warszawie
(43026) - Osrodek Badan Klinicznych Allmedica
Investigator: Dr. Mikolaj Krzyzanowski (mikolaj.krzyzanowski@gmail.com, 0048 600 616769)
Study Coordinator: Patrycja Lesnicka (patrycja.lesnicka@allmedica.pl, 0048 575 886613)
(43029) - IP Clinic, Lodz, 90-752
(43031) - Centrum Medyczne Grunwald, Poznan, 60-369
(43032) - Medicome Sp. z o.o., Oswiecim, 32-600
(43034) - Amicare Sp. z o.o. Sp.k, Lodz, 90-644
Study Coordinator: Maria Michalak (m.michalak@amicare.pl, 0048 42 6394944)
(43036) - Wip Warsaw Ibd Point, Warszawa, 00-728
(43037) - Landa-Specjalistyczne Gabinety Lekarskie, Krakow, Poland, 31-156
Investigator: Dr. Katarzyna Landa (landa@smo.com.pl)
Study Coordinator I: Justyna Targosz (targosz@smo.com.pl, 0048 508 790106)
Study Coordinator II: Julia Szczepanek (szczepanek@smo.com.pl, 0048 508 790106)
(43038) - Trialmed CRS, Piotrkow Trybunalski, 97-300
Study Coordinator: Piotr Pokojowczyk (piotr.pokojowczyk@wp.pl, 0048 510 945166)
(43039) - ETG Zamosc, Zamosc, 22-400
(43040) - PlanetMed sp. z o.o., Wroclaw, 52-210
(43041) - Specjalistyczne Gabinety Lekarskie Body Clinic, Warszawa, 03-712
(43042) - Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska, Wroclaw, 51-162
Study Coordinator: Katarzyna Okrzesa (okrzesa.katarzyna@cbk.wroc.pl, 0048 530 898161)
(43043) - Kiepury Clinic MAŁGORZATA JARNOT SPECJALISTYCZNA PRAKTYKA GINEKOLOGICZNO-POŁOŻNICZA
Spain
Hospitals:
(47005) - Hospital Universitario La Paz, Madrid, 28046
(47006) - Hospital Universitario de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Las Palmas, 35019
Investigator: Dr. Daniel Ceballos (investigacion.dig.negrino@gmail.com, 928 449676)
(47010) - Hospital General de Tomelloso, Tomelloso, Ciudad Real, 13700
Investigator: Dr. Alfredo J. Lucendo (ajlucendo@sescam.jccm.es)
Study Coordinator: Sousoles R. Tamarit (stamarit@sescam.jccm.es, 926 525928)
(47013) - Corporacio Sanitaria Parc Tauli
(47019) - Hospital Marina Baixa, Villajoyosa, Alicante, 03570
Switzerland
Hospitals:
(49004) - Inselspital - Universitaetsspital Bern
Investigator: Dr. Benjamin Misselwitz (benjamin.misselwitz@insel.ch)
Study Coordinator: Sandra Wyss (sandra.wyss@insel.ch)
(49008) - Universitaetsspital Basel
UK
Hospitals:
(52004) - Norfolk and Norwich University Hospital
(52005) - Yeovil District Hospital, Yeovil, Somerset, BA21 4AT
Investigator: Dr. Katie Smith
Study Coordinator: Amanda Roberts (clinical.research@ydh.nhs.uk, 01935 384854)
(52009) - Guys and St. Thomas NHS Foundation Trust, Lambeth, Greater London, SE1 7EH
(52011) - St James's University Hospital
(52012) - Central Middlesex Hospital
(52013) - Royal Liverpool University Hospital
Project date: August, 2022